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TB-500 (Thymosin Beta-4)

Peptide

Thymosin Beta-4

TB-500 acts systemically (whole body), unlike BPC-157 (local). The BPC-157 + TB-500 stack is the most effective injury-recovery protocol available.

Half-life

Quelques heures

Detection

Non détecté

Injectable

Dosages

Beginner2,0–2,5 mg/sem
Intermediate2,5–5 mg/sem
Advanced5–10 mg/sem
Female2-5 mg/week

Frequency : 2× / week (acute phase), 1× / week (maintenance)

Effects

  • Systemic tissue repair
  • Recovery of muscles/tendons/ligaments
  • Increased flexibility
  • Anti-inflammatory
  • Cellular growth

Side effects

  • Mild lethargy post-injection
  • Potential tumor growth (caution)

Support supplements

BPC-157 (synergistic)

Synergies & stacks

BPC-157 ++MK-677

Avoid

  • Oncological history

AnaProtoKol is a health and performance tracking tool. This information is provided for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any protocol.

Sources

Studies and scientific publications this guide relies on.

  1. Goldstein AL, Hannappel E, Kleinman HK (2005). Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine. doi: 10.1016/j.molmed.2005.07.004

    Revue mécanistique de référence : thymosine bêta-4 (TB-4, dont TB-500 est le fragment commercial) est une protéine séquestrante de l'actine G, libérée par les plaquettes et macrophages au site de lésion — stimule angiogenèse, migration kératinocytes et cellules endothéliales, réduit inflammation et fibrose.

  2. Crockford D, Turjman N, Allan C, et al. (2010). Thymosin beta4: structure, function, and biological properties supporting current and future clinical applications. Annals of the New York Academy of Sciences. doi: 10.1111/j.1749-6632.2010.05492.x

    Revue sur la thymosine bêta-4 : essais cliniques précoces en cicatrisation cutanée, ulcères veineux et lésions cornéennes — démonstration de la tolérance acceptable en administration topique ou systémique chez l'humain.

  3. Seiwerth S, Rucman R, Turkovic B, et al. (2018). BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing. Current Pharmaceutical Design. doi: 10.2174/1381612824666180712110447

    Synthèse mécanistique : TB-500 et BPC-157 sont les deux peptides de réparation les plus étudiés en préclinique, avec des mécanismes complémentaires (BPC-157 local, TB-500 systémique via la circulation sanguine).

  4. Pope HG Jr, Wood RI, Rogol A, et al. (2014). Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement. Endocrine Reviews. doi: 10.1210/er.2013-1058

    Énoncé Endocrine Society : peptides de réparation (BPC-157, TB-500) sont marqués par la rareté des données cliniques humaines et le signal théorique d'augmentation de la prolifération cellulaire — précaution oncologique formelle.

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AnaProtoKol is a health and performance tracking tool. This information is provided for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any protocol.