Oxandrolone (Var)
Oral steroidVar · Oxandrolone
One of the most popular oral steroids. Very well tolerated compared to other orals. Excellent for strength and cutting. Widely used by women at low doses. Expensive.
Half-life
9 heures
Detection
3 semaines
Anabolic ratio
322
Androgenic ratio
24
Dosages
| Beginner | 20–40 mg/j |
| Intermediate | 40–60 mg/j |
| Advanced | 60–100 mg/j |
| Female | 5-20 mg/day (well tolerated) |
Frequency : 2× / day (morning and midday)
Effects
- Strength
- Cutting
- Hardness
- Vascularity
- Low water retention
Side effects
- Hepatotoxicity (moderate)
- HPTA shutdown
- Lipid panel (HDL crash)
- Mild hair loss
Support supplements
Synergies & stacks
Avoid
- Stacking with another hepatotoxic oral
- Duration > 8 weeks
Sources
Studies and scientific publications this guide relies on.
- Strawford A, Barbieri T, Van Loan M, et al. (1999). Resistance exercise and supraphysiologic androgen therapy in eugonadal men with HIV-related weight loss: a randomized controlled trial. JAMA. doi: 10.1001/jama.281.14.1282
RCT JAMA chez 24 hommes eugonadiques en perte de poids liée au VIH : oxandrolone 20 mg/j + entraînement résistance pendant 8 semaines augmente la masse maigre (+5,1 kg) et la force significativement plus que testostérone TRT seule, avec impact lipidique défavorable (HDL effondré) attendu.
- Wolf SE, Edelman LS, Kemalyan N, et al. (2006). Effects of oxandrolone on outcome measures in the severely burned: a multicenter prospective randomized double-blind trial. Journal of Burn Care & Research. doi: 10.1097/01.BCR.0000202620.55751.4F
RCT multicentrique double-aveugle (81 grands brûlés 20-60 % TBSA) : oxandrolone 10 mg ×2/j (20 mg/j) raccourcit la durée d'hospitalisation (31,6 vs 43,3 jours) — démonstration clinique de l'effet anti-catabolique à dose modeste.
- Kicman AT (2008). Pharmacology of anabolic steroids. British Journal of Pharmacology. doi: 10.1038/bjp.2008.165
Revue de pharmacologie : oxandrolone (Anavar) est un dérivé DHT alkylé 17α et 2-oxa, ratio anabolique/androgénique 322/24, demi-vie orale ~9 heures, non aromatisable, faible activité androgénique cutanée — profil compatible avec usage féminin à dose réduite.
- Niedfeldt MW (2018). Anabolic Steroid Effect on the Liver. Current Sports Medicine Reports. doi: 10.1249/JSR.0000000000000467
Revue clinique : élévation des transaminases sous oxandrolone, mais hépatotoxicité considérée comme la plus modérée parmi les oraux 17α-alkylés — surveillance ALAT/ASAT recommandée mais profil acceptable à doses thérapeutiques (20-40 mg/j).
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