---
title: "Anastrozole"
description: "The reference aromatase inhibitor (AI). Dose based on symptoms and ideally bloods. Target: keep estradiol between 20-40 pg/mL. Prefer Aromasin if cholesterol is problematic."
lang: en
dateModified: 2026-05-25
canonical: https://anaprotokol.com/en/molecule/anastrozole
---

# Anastrozole

The reference aromatase inhibitor (AI). Dose based on symptoms and ideally bloods. Target: keep estradiol between 20-40 pg/mL. Prefer Aromasin if cholesterol is problematic.

**Catégorie** : Anti-œstrogène & SERM
**Voie d'administration** : Oral
**Demi-vie** : 48 heures
**Détection** : 2 semaines
**Aromatisation** : Non
**Progestine** : Non
**Hépatotoxique** : Non
**PCT requise** : Non

**Autres noms** : Adex, Arimidex

## Effets
- Estrogen reduction
- Gyno prevention
- Reduced water retention

## Effets secondaires
- Joint pain (if estrogen too low)
- Low libido (if E2 crash)
- HDL↓
- Low mood

## Suppléments de soutien
- Omega-3
- Zinc

## Synergies
- Any aromatizing cycle (Test, Dbol, Deca)

## À éviter
- Overdosing (estrogen too low is worse than high)
- Non-aromatizing cycles (useless)

## Dosage masculin
- Débutant : 0,25 mg/EOD
- Intermédiaire : 0,5 mg/EOD
- Avancé : 0,5–1 mg/EOD

## Dosage féminin
Medical use only

**Fréquence** : EOD (based on E2 levels)